Update Rollup 22 for Exchange 2010 Service Pack 3 is now available. It contains 2 changes and 1 documented new fix and all previously released fixes and security updates for Exchange 2010 SP3. Note that mainstream support for Exchange 2010 has already ended.
- VC++ 2013 runtime library is now required.
- Added support for Windows Server 2016 domain controllers.
- KB4295751: EWS impersonation not working when accessing resource mailboxes in a different site in Exchange Server 2010 SP3
View: Description of Update Rollup 22 for Exchange Server 2010
Download: Update Rollup 22 For Exchange 2010 SP3 (KB4295699)
View: Blog post of the Exchange Team about Rollup 22 for Exchange Server 2010